Ana I. Caño-Delgado is a Distinguished Investigator and founder of PLANeT BIOTECH the first spin off at the Centre for Research in Agricultural Genomics (CRAG, Barcelona, Spain. She did a PhD in Biology at John Innes Centre (UK) and was a HFSPO Postdoctoral Fellow at Salk Institute (US). She is internationally recognized for publishing numerous high-impact scientific journals, has received awards in science and entrepreneurship and is an elected EMBO Member since 2016. She is considered one of the 500 most-influencing women in Spain. At CRAG, she leads the Brassinosteroid signaling group supported two consecutive times by the European Research Council (ERC) grants to engineering crops able to grow on severe drought. These achievements are the results of two decades of studies in plant steroid hormones, in which she pioneers the study of signaling mechanisms with cell-specificity. In the context of a climate emergency, her lab works for the translation of these results to crops, including social cereal Sorghum. In addition, Caño-Delgado is an engaged science communicator chasing two specific goals: encouraging women in science leadership and acceptance of genomic edition tools for sustainable agriculture.
We offer an internship opportunity in our laboratory focused on the intricate plant physiology and biochemistry of brassinosteroid receptor signaling, with a particular emphasis on the BRL3 receptor in Arabidopsis thaliana. This position is ideal for master or graduate students with a strong interest in plant biology, hormone signaling, and advanced molecular techniques.
The intern will engage in cutting-edge research aimed at elucidating the role of brassinosteroids receptors, specifically BRL3, in regulating cell-specific development, and stress responses. Their responsibilities will include biochemical assays of BRL3 signaling components, and RNA sequencing (RNA-seq) analysis of single-cell profiles associated with BRL3 signaling pathways. They will also investigate cell-type-specific signaling mechanisms activated by BRL3 to understand how these pathways influence physiological responses at the cellular level in response to stress.
In addition to hands-on laboratory work, you will assist in characterizing the morphological changes induced by BRL3 activation under various stress conditions. This may involve using imaging techniques and statistical analyses to assess plant phenotypes.
The ideal candidate should possess a foundational understanding of plant physiology and biochemistry, along with experience in molecular biology techniques such as PCR, RNA extraction, and bioinformatics analysis related to RNA-seq data. Strong analytical skills, attention to detail, and the ability to work collaboratively within a multidisciplinary team are essential.
This internship offers a unique opportunity to develop practical skills in experimental design, data analysis, and scientific communication. Interns will have the chance to present their findings at lab meetings and contribute to ongoing research projects that explore the significance of brassinosteroid signaling through receptors like BRL3 in plant adaptation and resilience.
If you are passionate about plant science and eager to delve into the complex world of brassinosteroids and their signaling mechanisms in Arabidopsis, we encourage you to apply for this enriching internship experience.
From June 9 to August 31, 2025 (adjustable at the discretion of the organisation)