The rise in heatwaves and drought severely affect the capacity of crops to retain water and capture CO2 during photosynthesis, resulting in global yield reductions. One of the most promising approaches to enhance crop production in these conditions is to modify the photosynthetic capacity of plants. Indeed, some lineages have evolved mechanisms like C4 photosynthesis and the Crassulacean acid metabolism (CAM) to cope with some of these aspects. C4 species are extremely efficient at CO2 fixation but vulnerable to severe drought. Meanwhile, CAM plants are less productive but very capable of coping with significant drought periods.
In this regard, our group is interested in understanding how global re-arrangements of gene regulatory networks have shaped the evolution of carbon concentrating mechanisms like C4 and CAM and to use this information to engineer novel photosynthetic pathways. To do so, we employ different genomics, phenomics and synthetic biology tools.
This approach seeks to address the critical issue of sustaining crop productivity in the face of changing environmental conditions.
In particular, our Program addresses the study of the regulation of isoprenoid and lignin biosynthetic pathways, the organization of the cell endomembrane system, the fixation of carbon through photosynthesis, and the development of microalgae as a bioengineering and synthetic biology platform. These pathways and processes impact yield, fruit and seed quality, nutritional content, digestibility, bioenergetic value, and tolerance to biotic and abiotic stress. Our work aims to develop technologies to reprogram plant cells, including the design of genetic circuits for fine tuning gene expression, the design of novel metabolic pathways, and the use of plant cells as biofactories to express molecules of therapeutic interest.
The experimental approaches emerge from the biochemistry, genetics, molecular, and cell biology fields, and include advanced plant/microalgae system methodologies with transcriptomic, proteomic and metabolomic analyses. A substantial part of the research activities is performed in well-established models (Marchantia or Arabidopsis), crop plants (tomato, rice, and maize), and microalgae (Chlamydomonas and Chlorella).
The objective of the internship is to help in our efforts to engineer plants with an improve photosynthetic pathway. You will learn the skills required for designing, building and testing different genetic circuits in plants.
From June 9 to August 31, 2025 (adjustable at the discretion of the organisation)