He obtained his Ph.D. as a computational biologist at POSTECH, South Korea. During my Ph.D. training, he actively participated in various research projects that required data interpretations, machine learning, and communication with experimental biologists. Next, he moved to Barcelona in Spain where he worked as a postdoctoral researcher at Prof. Luis Serranos Lab (CRG). Initially, his position was supported by the European collaborative research project (PRIMES), and then he obtained a Juan de la Cierva fellowship. During this period, he developed a novel high-throughput method to investigate hundreds of thousands of synthetic promoters, revealing key sequences that determine transcription efficiency in Mycoplasma pneumoniae (Nature Comm. 2017). Further, he developed another method to identify protein-protein and RNA-protein interactions at an ORFeome-wide scale (Nature Comm. 2018, Methods 2019). Later, he moved to POSTECH in Korea, working as a Research Assistant Professor with my own Research Fellow funding from the National Research Foundation of Korea.
As a Junior Group leader at the Centre for Research in Agricultural Genomics (CRAG), since September 2019, he has started his independent research group on Computational and Synthetic Biology, with the initial goal of developing a bioengineering platform for photosynthetic cell factories, using two novel methods he developed during his post-doc period. He has been awarded the Plan Estatal grant (PID2020-117772GA-I00) from the Spanish Government MINECO to fund the main project of the lab and Ramón y Cajal (RYC2020-028880-I).
During this first stage and adaption to the CRAG, he already lead many fruitful collaborations as a principal investigator (inter)nationally and it has recently been published two papers as a co-corresponding author (Metab Eng. 2022 and Nat Commun. 2022) and a corresponding paper (Journal of Experimental Botany 2023).
Among the most relevant achievements in his career he highlight the following:
(1) Studies of model bacterial translation regulation and development of 5 UTR design tools (2 papers)
(2) Studies of non-model bacterial transcription and translation regulation (3 papers)
(3) Studies of protein-protein and RNA-protein interactions (4 papers)
(4) protein-protein interactions with structural and evolutionary analysis (6 papers)
(5) Studies of Single/Multiple localized proteins and sub-organellar localization (4 papers)
(6) Structural and evolutionary analysis of enzyme and enzyme engineering (4 papers)
(7) Developing statistical tools for the analysis of aging data (6 papers)
(8) First author of 7 free/open-source software (OASIS, UTRDesigner, UTRLibrary, SAPIN, TAPAS, ELMSeq, recYnH)
(9) Awarded by several and prestigious competitive fellowships from national calls (Juan de la Cierva-incorporation, Research Fellow, a junior group leader from Severo Ochoa, Ramon y Cajal)
(10) Got R3 certification (2023/11/08) and passed the CSIC oposiciones exam (2023/11/15)
Plants are a primary source of nutrients, chemicals, and materials for humans. Our program aims to generate fundamental knowledge on plant physiology and metabolism and to use this knowledge to improve crops through plant synthetic and metabolic engineering approaches. We are interested in deciphering the control of primary and secondary metabolism for the production of high-quality bioproducts and the enhancement of plant performance and yield. Furthermore, by using a synthetic biology framework, we aim to contribute to the advancement of basic plant research and provide novel biotechnological tools.
We are looking for a Master level student in biochemistry, biotechnology or biomedicine to help with the characterization the effect of the co-culture of microalgae and E. coli on the generation of a bioluminescent signal. We are currently developing a bioluminescent E. coli strain containing the lux operon and want to test the effect that several strategies have in the improvement of the bioluminescent signal. One of these strategies is the co-culture of these bacterial strain with algae under different growing conditions. The selected candidate will learn about synthetic biology and transformation techniques in E. coli, vector design, molecular cloning (GoldenGate) and will work with bacteria and with algae, optimization of bioluminescence and bacteria and algae co-culture. English proficiency will be highly valued.
From June 9 to August 31, 2025 (adjustable at the discretion of the organisation)